Skinbase, the mutant mouse skin and hair pathology database was established to provide an image reference resource for the histopathology of skin and its associated structures in induced and spontaneous mutations of the laboratory mouse. The history of mouse genetics is full of examples of the importance of skin and hair phenotypes in the development of our current understanding of the function of many genes and increasingly the mouse has become the model organism of choice for improving our understanding of skin and hair biology in human conditions such as alopecia areata or ichthyosis.

The images presented here are indexed by the common name of the mouse allele. Annotation of the images provides a commentary on the features of the manifestations of the lesion in the skin and associated structures.

Some images of human lesions are included where a mutation of the orthologous gene was demonstrated in the mouse, but for more information about human skin lesions please consult the link list at the bottom of this page.

Adnexal Glands	Adrenocortical Dysplasia (acd) Chr8	Anatomic hair types
Annotated anatomy of the mouse nail	Annotated anatomy of the mouse vibrissa	Aryl Hydrocarbon receptor null (Ahr) Chr12
Asebia (Stearoyl-Coenzyme A Desaturase 1)	Beige Lysosomal trafficing regulator (Lyst-bg) Chr13	Caracul(Krt2-6g-ca) Chr15
Chronic Proliferative Dermatitis Mutation (cpdm) Chr15	Crinkled (Edaradd-cr) Chr13	Depilated (dep) Chr4 38.8cM
Downless (Edar-dl) Chr10	Epidermal Growth Factor Receptor (Egfr) Chr11	Ferrochelatase Deficiency(Fech) Chr18
Flaky Skin (fsn) Mutant Mouse Chr17	Fuzzy (fz) Chr1	Hair cycle
Matted (ma) and Flaky Tail (ft) Mutant Mice Chr3	Nails	Repeated Epilation (Er) Chr4
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This project is funded by the North American Hair Research Society