Pathbase: PB 94718


Pathbase Image PB 94718 submitted by helmholtz center munich, inst f radiation biology on 2011-12-21
EMAP / Embryonic stage,
tissue or post-natal age:
Genotype Status:Rb1-LoxP/+ x Cre+
MPATH / Pathology:MPATH 606 - neoplasia
Genetic Manipulation:bone conditional Rb1 del(Ex19) under Col1a1-Cre control
MA / Anatomical Site:MA 1432 - lumbar vertebra 5
Designated Allele Name:
Experimental Manipulation:Radiation
Description:Osteoblastic Osteosarcoma (High-grade, well-structured) originating from lumbar vertebrae, with infiltration of spinal nerve

Tumor induction after alpha-irradiation of bone using Thorium227 injection

Magnification:x 5

Further Information
Search MGI@Jax:Gene: Rb1
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