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Mouse Pathology On-Line

Courtesy of Dr Laurence Fiette and the EUROGEMS mouse pathology course

Mouse genetics

Jackson Lab Almost everything about http://www.jax.org/resources/index.html
MGI, Mouse Genome Informatics genetics. mutants etc http://www.informatics.jax.org/
MGI, mouse nomenclature home page Genes, alleles, mutations strains http://www.informatics.jax.org/mgihome/nomen/index.shtml
IMSR-International Mouse Strain Resource Genetic glossary http://www.informatics.jax.org/imsr/glossary.jsp
Lee Silver's Mouse genetics Web version of the from L. Silver, 1995 http://www.informatics.jax.org/silver/
Transgenic Animal Web Breeding suggestions http://www.med.umich.edu/tamc/breed.html

Phenotyping

SHIRPA protocols http://www.springerlink.com/media/4G117BNPNE4RYVCF4ECN/Contributions/E/5/P/8/E5P8BL1BRDBTPR58.pdf
Necropsy, trimming
EULEP, EUropean Late Effects Project Covelli's Necropsy protocol & pictures http://eulep.pdn.cam.ac.uk/Necropsy_of_the_Mouse/index_2004.php
Virtual Mouse Necropsy, NIAID, with drawings http://www.niaid.nih.gov/dir/services/animalcare/Mousenecropsy/necropsy.html
Eumorphia EC Integrated research programme http://www.eumorphia.org/EMPReSS/servlet/EMPReSS.frameset
RENI, Registry Nomenclature Information System Trimming guidelines http://www.item.fraunhofer.de/reni/trimming/TR_F.htm
Organ sampling & trimming Joint publication http://www.elsevier-deutschland.de/etp#
RITA & NACAD Groups Part 1, Part 2, Part 3 Exp Tox Pathol 2003, 55, 91 / 2004 55, 413 / 2004, 55, 433
Histological techniques Immunoportal IHC, ISH protocols, downloads, links http://www.immunoportal.com
Protocols on line Useful links research protocols http://www.protocol-online.org/
University of Utah Histology procedures http://www-medlib.med.utah.edu/WebPath/HISTHTML/MANUALS/MANUALS.html
University of Columbia-Medical School Various links to protocols http://icg.cpmc.columbia.edu/cattoretti/Protocol/Links.html
University of Bristol Histological techniques, simple http://www.bris.ac.uk/Depts/PathAndMicro/CPL/histmeth.htm
DAKO Handbook
Handbook about basic IHC
http://www.dakocytomation.us/index/us_support_literature_index/
us_support_literature_immhandbook.htm
University of Columbia-Medical School List of Ab for mouse tissues http://Antibodies_for_mouse_IHC.html
PHL murine IHC database Searchable DTB, technical information http://web.ncifcrf.gov/rtp/lasp/phl/immuno/
NIEHS-Laboratory of Experimental Pathology Technical information, images http://dir.niehs.nih.gov/dirlep/immuno/
MTB-Jackson Lab Searchable database http://tumor.informatics.jax.org/FMPro?-db=Image&-format=pathology_search.html&-view
technical information, images  

Phenotyping (following)

Academic phenotyping labs German Mouse Clinic GSF, Munich http://www0.gsf.de/ieg/gmc/index.html
Institut Clinique de la Souris Strasbourg, France http://www-mci.u-strasbg.fr/ao.html
Mutant Mouse Pathology Laboratory University of California, Davis, USA http://tgmouse.compmed.ucdavis.edu/HistoLab/
University of Cornell GEM Phenotyping Core Facilitty http://www.med.cornell.edu/research/cores/gem/
NCI Pathology & Histotechnology Laboratory Frederick, USA http://web.ncifcrf.gov/rtp/lasp/phl/
Yale University, USA http://info.med.yale.edu/yarc/mousephenotype.htm
Ohio State University USA http://www.mousepheno.osu.edu/
ULAM, Unit for laboratory Animal Medicine University of Michigan, USA http://www.ulam.umich.edu/services/pathcons.htm
RADIL, Research Animal Diagnostic Laboratory University of Missouri, USA http://www.radil.missouri.edu/info/diagtesting/services/pathology.asp
Rodent Phenotyping Center John Hopkins Medicine, Maryland http://www.hopkinsmedicine.org/comparativemedicine/phenocenter/
Private Frimorfo Fribourg, Switzerland http://www.frimorfo.com
Charles River Laboratories USA, Europe http://www.criver.com/SRM/tgs/index.html
Taconic USA http://www.taconic.com/

Searching for my mouse

Searchable DTB MGI-Mouse Genome Informatics-Jackson http://www.informatics.jax.org/
CGMCC- Center Genome Mouse Friedberg http://niehs.nih.gov/cgmcc/friedsch.htm
Phenome database-Jackson Phenotypic & genotypic data http://aretha.jax.org/pub-cgi/phenome/mpdcgi?rtn=docs/home
ILAR-Institute for Laboratory Animal research National Academy Science, models list http://dels.nas.edu/ilar/ext_search.asp
Mouse Tumor Biology Database Tumor search, strain search http://tumor.informatics.jax.org/FMPro?-db=TumorInstance&-format=tumor_search.html&-view
Frontiers in Bioscience Various topics including KO DTB http://bioscience.org/
Academic resources & repositories IFMR-International Federation of Mouse Resources Consortium USA-Canada-Europe-Japon http://www.informatics.jax.org/imsr/ifmr.html
IMSR-International Mouse Strain Resource http://www.informatics.jax.org/imsr/index.jsp
IMR-Induced Mutant Resource-Jackson http://www.jax.org/imr/notes.html
MMHCC-Mouse Models of Human Cancers Consortium- NCI http://mouse.ncifcrf.gov/
MMRRC-Mouse Mutant Regional Resource Center Consortium http://www.MMRRC.org
ORNL-Oak Ridge National Laboratory http://www.bio.ornl.gov/mouse/
RIKEN Institute Bioresource Center Large scale mutagenesis programme http://www.gsc.riken.go.jp/Mouse/
EMMA-European Mouse Mutant Archive European Consortium http://www.emma.rm.cnr.it
MGU- Mouse Genetics Unit MRC Harwell Mutagenesis Programme http://www.mgu.har.mrc.ac.uk/facilities/stocklist/search.html
CMHD-Centre For Modelling Human Diseases Different research areas, Toronto http://www.cmhd.ca/
JMSR-Japan Mouse Strain Resource http://shigen.lab.nig.ac.jp/mouse/jmsr/strains.jsp
CARD R-BASE- Center for Animal Resource & Development, Japan http://cardb.cc.kumamoto-u.ac.jp/transgenic/about.jsp
MMCDD-Mouse Mutagenesis Center for Developmental Defects http://www.mouse-genome.bcm.tmc.edu/ENU/ENUMutantSources.asp
  Baylor College of Medecine Genetically-Engineered%20Mice.html
TMGC-Tennessee Mouse Genome Consortium 88 mutants defined http://tnmouse.org/
Neuromice Development, distribution neuro models http://www.neuromice.org

Searching for my mouse (following)

Private Charles River Laboratories http://www.criver.com
Taconic http://www.taconic.com/healthtesting/test_panels.htm
Harlan http://www.harlan.com/
Lexicon http://www.lexicon-genetics.com/index.php
Xenogen http://www.xenogen.com

Pathology of GEMS

Images Pathbase DTB histopatho mutants & GEMS http://eulep.pdn.cam.ac.uk/
MMHCC Normal histo, & neoplasms http://imagearchive.compmed.ucdavis.edu/
The Visible Mouse Histo, patho prostate, mammary, ovary http://ccm.ucdavis.edu/tvmouse/
Mouse Tumor Biology Database (MTB) Jackson's DTB on tumors http://tumor.informatics.jax.org/FMPro?-db=TumorInstance&-format=about_mtb.html&-findany
 
Lesions of genetically engineered mice http://dir.niehs.nih.gov/dirlep/genmice2/open_me.htm
Pathology & Biology of Genetically-Engineered Mice NIAID,-NIH, major links http://niaid.nih.gov/dir/services/animalcare/VetPathology/Genetically-Engineered%20Mice.html
 
RENI pathology mouse Classification of tumors, glossary http://www.ita.fhg.de/reni/index.htm
Infectious diseases Tutorial from Steve Barthold http://www.afip.org/vetpath/POLA/micerat.txt

Comparative Pathology

MMHCC models Reviews comparative patho http://emice.nci.nih.gov/
DHMD, Dysmorphic Human-Mouse Homology Database http://www.hgmp.mrc.ac.uk/DHMHD/dysmorph.html
Recommendations Pubmed reference http://www.ncbi.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=
Lymphoid organs Bethesda classification PubMed&list_uids=12070034&dopt=Abstract
Non lymphoid hematopoietic Bethesda classification PubMed&list_uids=12070033&dopt=Abstract
Mammary tumors Anannapolis meeting PubMed&list_uids=10713680&dopt=Abstract
Neuropathology Neuropatho of GEMS PubMed&list_uids=12386807&dopt=Abstract
Mouse models of intestinal cancer Consensus report & recommendations PubMed&list_uids=12612914&dopt=Abstract

Sites dedicated to specific organs

Mammary gland UC Davis Mouse Mammary Gland Site http://tgmouse.compmed.ucdavis.edu/
Slides from GEMS mammary tumors http://pathology.ucdavis.edu/tgmice/jaxworkshop/syllabus/frameset1.html
MMPL Mouse http://mammary.nih.gov/tools/index.html
Mammary gland development database    http://ana.ed.ac.uk/anatomy/database/mammbase/mammhome.html

Sites dedicated to specific organs (following)

Neurology Neuroanatomy Lab resource Appendice Numerous links about nervous system http://isc.temple.edu/neuroanatomy/lab/embryo_new
High resolution mouse brain atlas Wonderful atlas http://www.hms.harvard.edu/research/brain/atlas.html#
MBL-Mouse Brain Library Very interesting too, atlas http://mbl.org/
Neuropath http://www.neuropat.dote.hu/patholog.htm
Neuropheno tenessee http://neurophenotyping.utmem.edu/index2%20.html
Miscellaneous Glandular organs development database  Links to kidney, saliv. gland, lung sites http://www.ana.ed.ac.uk/anatomy/database/orghome.html
Kidney development database Large information, ref not updated http://golgi.ana.ed.ac.uk/kidhome.html kidney
Tooth http://bite-it.helsinki.fi/
Immune systems mutants Harvard http://immunology.tch.harvard.edu/
Lymphoma leukemia http://tgmouse.compmed.ucdavis.edu/lymleuk2/mouse.htm
CVCGD-Cardiovascular comparative genomics database http://pga.lbl.gov/cvcgd.html
Skin Nice pictures, skin mutants http://eulep.pdn.cam.ac.uk/~skinbase/index.php
Leiden muscular dystrophies http://www.dmd.nl

Histology & Pathology on the Web

Histology NIH histology atlas http://histology.nih.gov/
Deltagen histology atlas http://www.deltagen.com/target/histologyatlas/HistologyAtlas.html
Texas histology CD ROM for sale http://home.austin.rr.com/texashistopages/
University Illinois Atlas of Histology http://www.med.uiuc.edu/histo/small/atlas/index.htm
University Iowa Virtual slidebox http://www.path.uiowa.edu/virtualslidebox
Pathology Pathopic http://alf3.urz.unibas.ch/pathopic/e/intro.html
Pathweb http://pathwe.uchc.edu/
Bioscience Tumor atlas http://www.bioscience.org/atlases/tumpath/tumpath.htm
Brown Medical School Digital pathology http://www.brown.edu/course/digital_path/nonflash.htm
University of Washington http://www.pathology.washington.edu/about/education/gallery
Links Martindale's virtual medical center Numerous links http://www.martindalecenter.com/Reference_3_LabP.html
University of Arizona Links http://swehsc.pharmacy.arizona.edu/exppath/micro/histology.html
Pathmax Links http://www.pathmax.com/main.html

Embryology

EMAP Edinburgh Mouse Atlas Project Wonderful 2D, 3D http://genex.hgu.mrc.ac.uk/
Bioscience Atlas of human embryogenesis http://bioscience.org/flash/embryo/embryo.htm
Multidimensional human embryo http://embryo.soad.mich.edu/
The Visible Embryo http://www.visembryo.com/baby/index.html
Human Embryology Book chapters with animations http://cna.uc.edu/embryology/

Links

Netvet http://netvet.wustl.edu/rodents.htm
RENI links http://www.item.fraunhofer.de/reni/index.htm

Mail lists, forums

Whole Mouse Catalog http://www.muridae.com/wmc/
Transgenic list http://mailman.ic.ac.uk/mailman/listinfo/transgenic-list
Histonet http://www.histosearch.com/histonet.html
PHENOME-LISTservice discussion of strain characterization, phenotypic data &related topics. http://aretha.jax.org/pub-cgi/phenome/mpdcgi?rtn=docs/phenomelist
Bionet lists http://www.bio.net/archives.html


Mouse Molecular Genetics and Mutation Databases



Gene Expression Databases



Anatomy and Pathology



Links to Radiation Biology, Radiation Protection and Regulatory Agencies



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