Pathbase

Pathbase: PB 24190

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Pathbase Image PB 24190 submitted by The Netherlands Cancer Institute on 2004-05-18
Sex:Female
Gene:Msh2
Mdr
Strain:FVB
Organism:Mouse
EMAP / Embryonic stage,
tissue or post-natal age:
Genotype Status:Homozygous (Gene: Mdr)
Heterozygous (Gene: Msh2)
MPATH / Pathology:MPATH 134 - hyperplasia
Genetic Manipulation:Gene-knockout-deletion (Gene: Msh2)
Gene-knockout-deletion (Gene: Mdr)
MA / Anatomical Site:MA 324 - hepatobiliary system
Designated Allele Name:
Experimental Manipulation:
Description:Oval cell hyperplasia


Magnification:
Stain:H&E


Further Information
Gene Ontology Terms associated with the genes involved in this lesion may be searched on AMIGO by clicking on each GO ID number below:
Search AmiGO:GO ID: 0006810 - transport (Gene: Mdr)
Search AmiGO:GO ID: 0005524 - ATP binding (Gene: Mdr)
Search AmiGO:GO ID: 0005624 - membrane fraction (Gene: Mdr)
Search AmiGO:GO ID: 0016021 - integral to membrane (Gene: Mdr)
Search AmiGO:GO ID: 0042493 - response to drug (Gene: Mdr)
Search AmiGO:GO ID: 0004009 - ATP-binding cassette (ABC) transporter activity (Gene: Mdr)
Search AmiGO:GO ID: 0006298 - mismatch repair (Gene: Mdr)
Search AmiGO:GO ID: 0006298 - mismatch repair (Gene: Mdr)
Search AmiGO:GO ID: 0005215 - transporter activity (Gene: Mdr)
Search AmiGO:GO ID: 0045910 - negative regulation of DNA recombination (Gene: Msh2)
Search AmiGO:GO ID: 0005634 - nucleus (Gene: Msh2)
Search AmiGO:GO ID: 0006301 - postreplication repair (Gene: Msh2)
Search AmiGO:GO ID: 0007050 - cell cycle arrest (Gene: Msh2)
Search AmiGO:GO ID: 0008340 - determination of adult life span (Gene: Msh2)
Search AmiGO:GO ID: 0003684 - damaged DNA binding (Gene: Msh2)
Search MGI@Jax:Gene: Mdr
Search MGI@Jax:Gene: Msh2
NOTE: Not all terms are currently shared between Pathbase and the above databases, some searches may not produce returns, in which case users should use synonyms or more inclusive text terms to search manually!


Copyright
This image remains the property of the originating Institution and should not be modified, reproduced or disseminated without the express permission of the submitter.




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