Description

Oval cell hyperplasia

MPATH / Pathology

MPATH 134 - hyperplasia

Gene

Msh2
Mdr

sex

Female

strain

FVB

organism

Mouse

EMAP / Embryonic stage, tissue or post-natal age:

genotype status

Homozygous (Gene: Mdr)
Heterozygous (Gene: Msh2)

genetic manipulation

Gene-knockout-deletion (Gene: Msh2)
Gene-knockout-deletion (Gene: Mdr)

MA / Anatomical Site

MA 324 - hepatobiliary system

Designated Allele Name

Experimental Manipulation

Further info

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Copyright

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Gene Ontology

GO ID: 0006810 - transport (Gene: Mdr)GO ID: 0005524 - ATP binding (Gene: Mdr)GO ID: 0005624 - membrane fraction (Gene: Mdr)GO ID: 0016021 - integral to membrane (Gene: Mdr)GO ID: 0042493 - response to drug (Gene: Mdr)GO ID: 0004009 - ATP-binding cassette (ABC) transporter activity (Gene: Mdr)GO ID: 0006298 - mismatch repair (Gene: Mdr)GO ID: 0006298 - mismatch repair (Gene: Mdr)GO ID: 0005215 - transporter activity (Gene: Mdr)GO ID: 0045910 - negative regulation of DNA recombination (Gene: Msh2)GO ID: 0005634 - nucleus (Gene: Msh2)GO ID: 0006301 - postreplication repair (Gene: Msh2)GO ID: 0007050 - cell cycle arrest (Gene: Msh2)GO ID: 0008340 - determination of adult life span (Gene: Msh2)GO ID: 0003684 - damaged DNA binding (Gene: Msh2)

MGI:

Gene: Mdr

MGI:

Gene: Msh2