Description

Defect in Eye-lens development,
no lens induction at the placode stage,
mutation mapped to Mouse chromosome 19,
Marker intervall D19Mit21 - D19Mit10,
recessive transmission of phenotype,
complementation with Aphakia mutant
(Eyl-/- x Ak -/- F1 mice are affected),
Eyl-/- mice carry a frameshift mutation in Pitx3 gene

MPATH / Pathology

MPATH 86 - organ specific developmental defect

Gene

Pitx3

sex

Unknown

strain

C3H

organism

Mouse

EMAP / Embryonic stage, tissue or post-natal age:

EMAP 3980 - TS20,embryo

genotype status

Homozygous

genetic manipulation

Spontaneous-mutant

MA / Anatomical Site

MA 261 - eye

Designated Allele Name

Eyl

Experimental Manipulation

Further info

NOTE: Not all terms are currently shared between Pathbase and the above databases, some searches may not produce returns, in which case users should use synonyms or more inclusive text terms to search manually!

Copyright

This image remains the property of the originating Institution and should not be modified, reproduced or disseminated without the express permission of the submitter.

MGI:

Gene: Pitx3