Pathbase: PB 24087


Pathbase Image PB 24087 submitted by University of Cambridge on 2003-11-01
Strain:C57BL/6 CRL
EMAP / Embryonic stage,
tissue or post-natal age:
99994 - Newborn
Genotype Status:Wild-type
MPATH / Pathology:MPATH 458 - normal
Genetic Manipulation:None
MA / Anatomical Site:MA 1602 - lower jaw molar
Designated Allele Name:
Experimental Manipulation:
Description:Formation of alveoar bone septum in between the first and second molar in a 14 day post-natal mouse.
The alveolar bone at this stage of development is characterised by immature bone trabeculae where the individual trabeculae are lined with active osteoblasts. Note that the connective tissue adjacent to the osteoblasts is richly vascularised and that there are small areas of bone marrow associated with these structures.
This section has been immunohistochemically stained to reveal osteoclasts using antibodies to tartrate resistant acid phosphatase.
The osteoclasts (brown cells)lie closely apposed to the bone surface, some of them obviously active since associated with a lacunar area.


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