PB 24087

Date

2003-11-01

Magnification

Stain

H&E

Author

University of Cambridge

Series

Description

Formation of alveoar bone septum in between the first and second molar in a 14 day post-natal mouse.
The alveolar bone at this stage of development is characterised by immature bone trabeculae where the individual trabeculae are lined with active osteoblasts. Note that the connective tissue adjacent to the osteoblasts is richly vascularised and that there are small areas of bone marrow associated with these structures.
This section has been immunohistochemically stained to reveal osteoclasts using antibodies to tartrate resistant acid phosphatase.
The osteoclasts (brown cells)lie closely apposed to the bone surface, some of them obviously active since associated with a lacunar area.

MPATH / Pathology

MPATH 458 - normal

Gene

sex

Male

strain

C57BL/6 CRL

organism

Mouse

EMAP / Embryonic stage, tissue or post-natal age:

99994 - Newborn

genotype status

Wild-type

genetic manipulation

None

MA / Anatomical Site

MA 1602 - lower jaw molar

Designated Allele Name

Experimental Manipulation

Further info

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Copyright

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