Description

Patchy testicular atrophy caused by depletion of germ cells: Sertoli-cell-only syndrome.

MPATH / Pathology

MPATH 127 - atrophy

Gene

Gdnf

sex

Male

strain

C57BL6/J-Gdnf^tm1Uhb

organism

Mouse

EMAP / Embryonic stage, tissue or post-natal age:

genotype status

Heterozygous

genetic manipulation

Gene-knockout-deletion

MA / Anatomical Site

MA 412 - seminiferous tubule

Designated Allele Name

Experimental Manipulation

Further info

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Copyright

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Gene Ontology

GO ID: 0005160 - transforming growth factor-beta receptor binding GO ID: 0005615 - extracellular space GO ID: 0006916 - anti-apoptosis GO ID: 0007169 - transmembrane receptor protein tyrosine kinase signaling pathway GO ID: 0007179 - TGFbeta receptor signaling pathway GO ID: 0007399 - neurogenesis GO ID: 0007422 - peripheral nervous system development GO ID: 0007422 - peripheral nervous system development GO ID: 0009653 - morphogenesis GO ID: 0030432 - peristalsis

Search PubMed:

PubMed number: 10688798

MGI:

Gene: Gdnf