Pathbase: PB 195


Pathbase Image PB 195 submitted by Inst. of Biomedicine, Univ. of Helsinki on 2002-01-01
EMAP / Embryonic stage,
tissue or post-natal age:
Genotype Status:Heterozygous
MPATH / Pathology:MPATH 127 - atrophy
Genetic Manipulation:Gene-knockout-deletion
MA / Anatomical Site:MA 412 - seminiferous tubule
Designated Allele Name:
Experimental Manipulation:
Description:Patchy testicular atrophy caused by depletion of germ cells: Sertoli-cell-only syndrome.


Further Information
Gene Ontology Terms associated with the genes involved in this lesion may be searched on AMIGO by clicking on each GO ID number below:
Search AmiGO:GO ID: 0005160 - transforming growth factor-beta receptor binding
Search AmiGO:GO ID: 0005615 - extracellular space
Search AmiGO:GO ID: 0006916 - anti-apoptosis
Search AmiGO:GO ID: 0007169 - transmembrane receptor protein tyrosine kinase signaling pathway
Search AmiGO:GO ID: 0007179 - TGFbeta receptor signaling pathway
Search AmiGO:GO ID: 0007399 - neurogenesis
Search AmiGO:GO ID: 0007422 - peripheral nervous system development
Search AmiGO:GO ID: 0007422 - peripheral nervous system development
Search AmiGO:GO ID: 0009653 - morphogenesis
Search AmiGO:GO ID: 0030432 - peristalsis
Search PubMed:PubMed number: 10688798
Search MGI@Jax:Gene: Gdnf
NOTE: Not all terms are currently shared between Pathbase and the above databases, some searches may not produce returns, in which case users should use synonyms or more inclusive text terms to search manually!

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