Description

Open lens vesicle. 90% of homozygous mice are anophthalmic.

MPATH / Pathology

MPATH 473 - developmental cystic dysplasia

Gene

retina and anterior neural fold homeobox
Rax

sex

Unknown

strain

ZRDCT-AN-Rax^ey1

organism

Mouse

EMAP / Embryonic stage, tissue or post-natal age:

genotype status

Homozygous

genetic manipulation

Spontaneous-mutant

MA / Anatomical Site

MA 275 - lens

Designated Allele Name

eyeless 1
ey1

Experimental Manipulation

Further info

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Copyright

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Gene Ontology

GO ID: 0003677 - DNA binding GO ID: 0003700 - transcription factor activity GO ID: 0005634 - nucleus GO ID: 0005667 - transcription factor complex GO ID: 0006355 - regulation of transcription, DNA-dependent GO ID: 0007275 - development

MGI:

Gene: Rax

MGI:

Gene: retina and anterior neural fold homeobox