Description

Infiltrative basal cell carcinoma from female Ptch +/- mouse after irradiation with 4 Gy of X-rays.Immunohistochemistry for keratin 14.

MPATH / Pathology

MPATH 234 - basal cell carcinoma

Gene

Ptch

sex

Female

strain

(129SV-Ptch^tm1Zim;C57BL/6); CD1

organism

Mouse

EMAP / Embryonic stage, tissue or post-natal age:

99998 - Adult

genotype status

Heterozygous

genetic manipulation

Gene-knockout-deletion

MA / Anatomical Site

MA 517 - trunk skin

Designated Allele Name

Patched

Experimental Manipulation

Radiation

Further info

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Copyright

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Gene Ontology

GO ID: 0005887 - integral to plasma membrane GO ID: 0007226 - regulation of smoothened receptor by patched GO ID: 0008158 - patched receptor activity GO ID: 0016021 - integral to membrane GO ID: 0030326 - limb morphogenesis GO ID: 0040015 - negative regulation of body size

Mouse Phenome Database

MPD number: 5525

Search PubMed:

PubMed number: 12386820

MGI:

Gene: Ptch