Pathbase: PB 1229


Pathbase Image PB 1229 submitted by University of Cambridge on 2002-06-11
Strain:(129SV-Ptchtm1Zim;C57BL/6); CD1
EMAP / Embryonic stage,
tissue or post-natal age:
99998 - Adult
Genotype Status:Heterozygous
MPATH / Pathology:MPATH 234 - basal cell carcinoma
Genetic Manipulation:Gene-knockout-deletion
MA / Anatomical Site:MA 517 - trunk skin
Designated Allele Name:Patched
Experimental Manipulation:Radiation
Description:Infiltrative basal cell carcinoma from female Ptch +/- mouse after irradiation with 4 Gy of X-rays.


Further Information
Gene Ontology Terms associated with the genes involved in this lesion may be searched on AMIGO by clicking on each GO ID number below:
Search AmiGO:GO ID: 0005887 - integral to plasma membrane
Search AmiGO:GO ID: 0007226 - regulation of smoothened receptor by patched
Search AmiGO:GO ID: 0008158 - patched receptor activity
Search AmiGO:GO ID: 0016021 - integral to membrane
Search AmiGO:GO ID: 0030326 - limb morphogenesis
Search AmiGO:GO ID: 0040015 - negative regulation of body size
Search the Mouse Phenome Database:MPD number: 5525
Search PubMed:PubMed number: 12386820
Search MGI@Jax:Gene: Ptch
Images of the same study:Study number: 4
NOTE: Not all terms are currently shared between Pathbase and the above databases, some searches may not produce returns, in which case users should use synonyms or more inclusive text terms to search manually!

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