Pathbase

Pathbase Search

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203 image(s) found:

Accession NumberGene / PathologyDescriptionImage Thumbnail
PB 195 Gene:
Gdnf

Pathology:
MPATH 127 - atrophy
Patchy testicular atrophy caused by depletion of germ cells: Sertoli-cell-only syndrome.
PB 196 Gene:
Gdnf

Pathology:
MPATH 127 - atrophy
Disruption of spermatogenesis and accumulation of undifferentiated spermatogonia in GDNF overexpressing mice. Testicular morphology of GDNF-overexpressing mice is normal at birth. After 2 to 3 weeks, a chimeric histological pattern is observed. The t ...
PB 3267 Gene:
N/A

Pathology:
MPATH 4 - necrosis
CNS necrosis
PB 3268 Gene:
N/A

Pathology:
MPATH 58 - aplasia
Cerebellar aplasia
PB 3270 Gene:
N/A

Pathology:
MPATH 4 - necrosis
Cerebellar necrosis. 3 weeks old.
PB 3271 Gene:
N/A

Pathology:
MPATH 58 - aplasia
Cerebellar aplasia
PB 3272 Gene:
N/A

Pathology:
MPATH 4 - necrosis
MPATH 506 - histiocytic sarcoma
Histiocytic sarcoma in the liver with accompanying necrosis.
PB 3273 Gene:
N/A

Pathology:
MPATH 4 - necrosis
MPATH 107 - congestion
Hepatic congestion and necrosis
PB 3280 Gene:
N/A

Pathology:
MPATH 553 - neuritis
Neuritis of the sciatic nerve
PB 3284 Gene:
N/A

Pathology:
MPATH 184 - sclerosis
Sclerosing lymphadenopathy. 8 months old male.
PB 3287 Gene:
N/A

Pathology:
MPATH 64 - developmental dysplasia
Cerebellar micropolygyria / polymicrogyria
PB 3291 Gene:
N/A

Pathology:
MPATH 200 - myositis
Myositis with fatty infiltration
PB 3292 Gene:
N/A

Pathology:
MPATH 200 - myositis
Myositis, degeneration of skeletal muscle fibres
PB 3294 Gene:
N/A

Pathology:
MPATH 7 - coagulation necrosis
Liver coagulative necrosis. 3 months old.
PB 3295 Gene:
N/A

Pathology:
MPATH 200 - myositis
Myositis
PB 3297 Gene:
N/A

Pathology:
MPATH 134 - hyperplasia
Pancreatic islet cell hyperplasia
PB 3324 Gene:
N/A

Pathology:
MPATH 3 - apoptosis
Apoptotic peripheral retinal ganglion cells. 10 days old.
PB 3336 Gene:
N/A

Pathology:
MPATH 134 - hyperplasia
Pulmonary adenomatous hyperplasia
PB 3337 Gene:
N/A

Pathology:
MPATH 15 - general degenerative process
MPATH 62 - cyst
Pituitary cystic degeneration
PB 3341 Gene:
N/A

Pathology:
MPATH 181 - fibrosis
Hepatic fibrosis
PB 3342 Gene:
N/A

Pathology:
MPATH 212 - inflammation
Pyelonephritis
PB 3349 Gene:
N/A

Pathology:
MPATH 4 - necrosis
Focal acute renal tubular necrosis
PB 3350 Gene:
N/A

Pathology:
MPATH 214 - chronic inflammation
MPATH 553 - neuritis
Chronic neuritis
PB 3353 Gene:
N/A

Pathology:
MPATH 181 - fibrosis
Lymph node fibrosis. 7 months old.
PB 3355 Gene:
N/A

Pathology:
MPATH 4 - necrosis
Testicular necrosis
PB 3359 Gene:
N/A

Pathology:
MPATH 194 - immune mediated disease
MPATH 214 - chronic inflammation
Chronic interstitial nephritis
PB 3363 Gene:
N/A

Pathology:
MPATH 181 - fibrosis
Lung fibrosis. 2 months old.
PB 3366 Gene:
N/A

Pathology:
MPATH 134 - hyperplasia
MPATH 285 - intraductal papilloma
Ureteric papillomatous hyperplasia
PB 3369 Gene:
N/A

Pathology:
MPATH 212 - inflammation
Otitis media. 1 month old.
PB 3371 Gene:
N/A

Pathology:
MPATH 26 - alopecia
Dorsal skin alopecia areata. 6 months old.
PB 3373 Gene:
N/A

Pathology:
MPATH 196 - dermatitis
MPATH 217 - ulcerative inflammation
Ulcerative dermatitis. 2 months old female.
PB 3374 Gene:
N/A

Pathology:
MPATH 212 - inflammation
Otitis interna. 5 months old.
PB 3375 Gene:
N/A

Pathology:
MPATH 201 - vasculitis
Polyarteritis nodosa. 9 months old.
PB 3386 Gene:
N/A

Pathology:
MPATH 62 - cyst
MPATH 473 - developmental cystic dysplasia
Polycystic kidney disease. 123 days old.
PB 3396 Gene:
N/A

Pathology:
MPATH 15 - general degenerative process
Testicular degeneration. 180 days old.
PB 3401 Gene:
N/A

Pathology:
MPATH 134 - hyperplasia
Pancreatic islet cell hyperplasia
PB 3409 Gene:
N/A

Pathology:
MPATH 64 - developmental dysplasia
Retinal dysplasia. 42 days old.
PB 3415 Gene:
N/A

Pathology:
MPATH 134 - hyperplasia
Eye anterior proliferation. 2.5 months old.
PB 3418 Gene:
N/A

Pathology:
MPATH 215 - granulomatous inflammation
Pyogenic granuloma of the cornea
PB 3419 Gene:
N/A

Pathology:
MPATH 212 - inflammation
Cornea inflammation
PB 3421 Gene:
N/A

Pathology:
MPATH 212 - inflammation
MPATH 554 - dystrophy
Follicular dystrophy and steatitis. 6 months old.
PB 3426 Gene:
N/A

Pathology:
MPATH 15 - general degenerative process
Purkinje cell degeneration
PB 3444 Gene:
N/A

Pathology:
MPATH 4 - necrosis
Cerebral necrosis. 8 days old.
PB 3445 Gene:
N/A

Pathology:
MPATH 4 - necrosis
Cerebral necrosis. 8 days old.
PB 3446 Gene:
N/A

Pathology:
MPATH 4 - necrosis
Cerebral necrosis. 8 days old.
PB 3456 Gene:
N/A

Pathology:
MPATH 15 - general degenerative process
MPATH 127 - atrophy
Testicular degeneration
PB 3458 Gene:
N/A

Pathology:
MPATH 213 - acute inflammation
Acidophilic macrophage pneumonia
PB 3459 Gene:
N/A

Pathology:
MPATH 4 - necrosis
Liver necrosis. 5 months old male.
PB 3462 Gene:
N/A

Pathology:
MPATH 214 - chronic inflammation
Chronic pancreatic islitis
PB 3466 Gene:
N/A

Pathology:
MPATH 127 - atrophy
Atrophic optic nerve. 22 months old.
PB 3467 Gene:
N/A

Pathology:
MPATH 127 - atrophy
Atrophic optic nerve. 22 months old.
PB 3489 Gene:
Notch4

Pathology:
MPATH 4 - necrosis
MPATH 549 - carcinoma
Solid tubular mammary carcinoma with necrosis. 7 months old.
PB 3490 Gene:
N/A

Pathology:
MPATH 4 - necrosis
MPATH 268 - adenocarcinoma
Solid tubular mammary carcinoma with necrosis. 7 months old.
PB 3506 Gene:
TGFA

Pathology:
MPATH 181 - fibrosis
Severe pancreatic fibrosis. 5 months old.
PB 3507 Gene:
TGFA

Pathology:
MPATH 181 - fibrosis
Severe pancreatic fibrosis. 5 months old.
PB 3518 Gene:
Thy1

Pathology:
MPATH 214 - chronic inflammation
Cardiac polyarteritis nodosa. 9 months old male.
PB 3519 Gene:
Thy1

Pathology:
MPATH 214 - chronic inflammation
Heart polyarteritis nodosa. 9 months old male.
PB 3520 Gene:
Thy1

Pathology:
MPATH 214 - chronic inflammation
Heart polyarteritis nodosa. 9 months old.
PB 3521 Gene:
Thy1

Pathology:
MPATH 214 - chronic inflammation
Heart polyarteritis nodosa. 9 months old male.
PB 3522 Gene:
Vldlr

Pathology:
MPATH 215 - granulomatous inflammation
Skin trichogranuloma. 2 months old male.
PB 3523 Gene:
Vldlr

Pathology:
MPATH 554 - dystrophy
Skin follicular dystrophy. 1 month old female.
PB 3524 Gene:
Vldlr

Pathology:
MPATH 554 - dystrophy
Skin follicular dystrophy. 1 month old.
PB 3525 Gene:
Vldlr

Pathology:
MPATH 554 - dystrophy
Skin follicular dystrophy. 1 month old female.
PB 3526 Gene:
Apoe

Pathology:
MPATH 28 - atherosclerosis
Aortic atherosclerosis. 5 months old.
PB 3527 Gene:
Apoe

Pathology:
MPATH 28 - atherosclerosis
Aortic atherosclerosis. 5 months old.
PB 3528 Gene:
Apoe

Pathology:
MPATH 28 - atherosclerosis
Aortic atherosclerosis. 5 months old.
PB 13266 Gene:
Odc

Pathology:
MPATH 62 - cyst
MPATH 196 - dermatitis
MPATH 217 - ulcerative inflammation
Utricle ulcerative dermatitis. 9 months old male. See description of MGI:1930205.
PB 13267 Gene:
Odc

Pathology:
MPATH 62 - cyst
MPATH 196 - dermatitis
MPATH 217 - ulcerative inflammation
Utricle ulcerative dermatitis. 9 months old. See desciption of MGI:1930205.
PB 13268 Gene:
Odc

Pathology:
MPATH 62 - cyst
MPATH 196 - dermatitis
MPATH 217 - ulcerative inflammation
Utricle ulcerative dermatitis. 9 months old. See description of MGI:1930205.
PB 13289 Gene:
N/A

Pathology:
MPATH 127 - atrophy
Pancreatic acinar atrophy
PB 13317 Gene:
N/A

Pathology:
MPATH 4 - necrosis
Lung necrosis. 2 weeks old.
PB 13333 Gene:
N/A

Pathology:
MPATH 213 - acute inflammation
Pneumonia due to aspiration of feed/bedding
PB 13334 Gene:
N/A

Pathology:
MPATH 213 - acute inflammation
Pneumonia due to aspiration of feed/bedding. The lesion viewed using polarized light the illuminate foreign body.
PB 13354 Gene:
Lepr

Pathology:
MPATH 14 - process of degenerative change
The two db/db male mice shown here , 15-17 weeks old (JAX # 000642) had all four distal limb joints swollen. There was no damage to any other bones. This phenotype has not been previously reported. Note that this strain may also contain the recessive ...
PB 13445 Gene:
N/A

Pathology:
MPATH 215 - granulomatous inflammation
Pyogenic granuloma of the cornea
PB 13446 Gene:
N/A

Pathology:
MPATH 212 - inflammation
MPATH 554 - dystrophy
Follicular dystrophy and steatitis. 6 months old.
PB 13452 Gene:
N/A

Pathology:
MPATH 15 - general degenerative process
Purkinje cell degeneration
PB 13459 Gene:
Fech

Pathology:
MPATH 196 - dermatitis
MPATH 217 - ulcerative inflammation
Ear focal ulcerative dermatitis. 6 months old female.
PB 13460 Gene:
Fech

Pathology:
MPATH 181 - fibrosis
MPATH 214 - chronic inflammation
Fibrosing cholangitis. 3-4 weeks old
PB 13461 Gene:
Fech

Pathology:
MPATH 181 - fibrosis
MPATH 214 - chronic inflammation
Fibrosing cholangitis. 3-4 weeks old
PB 13529 Gene:
N/A

Pathology:
MPATH 14 - process of degenerative change
Cytomegaly and karyomegaly of duct cells in caudal epididymis
PB 13530 Gene:
N/A

Pathology:
MPATH 14 - process of degenerative change
Cytomegaly and karyomegaly of duct cells in caudal epididymis
PB 13552 Gene:
chronic proliferative dermatitis
cpdm

Pathology:
MPATH 134 - hyperplasia
MPATH 196 - dermatitis
Chronic proliferative dermatitis mice develop a chronic persistent dermatitis characterized clinically by pruritus and scaling and light microscopically by epidermal hyperplasia and infiltration of the skin by eosinophils and macrophages
PB 13553 Gene:
chronic proliferative dermatitis
cpdm

Pathology:
MPATH 134 - hyperplasia
MPATH 196 - dermatitis
Chronic proliferative dermatitis mice develop a chronic persistent dermatitis characterized clinically by pruritus and scaling and light microscopically by epidermal hyperplasia and infiltration of the skin by eosinophils and macrophages
PB 13554 Gene:
N/A

Pathology:
MPATH 214 - chronic inflammation
Dextran-sodium sulfate (DSS) induced chronic colitis
PB 13594 Gene:
hair patches
Hpt

Pathology:
MPATH 184 - sclerosis
Glomerulosclerosis
PB 13595 Gene:
hair patches
Hpt

Pathology:
MPATH 184 - sclerosis
Glomerulosclerosis
PB 13599 Gene:
hid

Pathology:
MPATH 58 - aplasia
The medullary cells are large and elongated, and irregularly packed into the medullary space
PB 13600 Gene:
hid

Pathology:
MPATH 58 - aplasia
The medullary cells are large and elongated, and irregularly packed into the medullary space
PB 13666 Gene:
Rax
retina and anterior neural fold homeobox

Pathology:
MPATH 58 - aplasia
MPATH 473 - developmental cystic dysplasia
Open lens vesicle. 90% of homozygous mice are anophthalmic.
PB 13667 Gene:
Rax
retina and anterior neural fold homeobox

Pathology:
MPATH 473 - developmental cystic dysplasia
Open lens vesicle. 90% of homozygous mice are anophthalmic.
PB 13760 Gene:
RAR-related orphan receptor alpha
Rora

Pathology:
MPATH 127 - atrophy
Cerebellar atrophy
PB 13761 Gene:
RAR-related orphan receptor alpha
Rora

Pathology:
MPATH 127 - atrophy
Cerebellar atrophy
PB 13762 Gene:
RAR-related orphan receptor alpha
Rora

Pathology:
MPATH 127 - atrophy
Cerebellar atrophy
PB 13763 Gene:
RAR-related orphan receptor alpha
Rora

Pathology:
MPATH 127 - atrophy
Cerebellar atrophy
PB 13764 Gene:
glycerol-3-phosphate dehydrogenase 1 (soluble)
Gpd1

Pathology:
MPATH 214 - chronic inflammation
MPATH 217 - ulcerative inflammation
Focal ulcerative colitis. 1 year old.
PB 13841 Gene:
N/A

Pathology:
MPATH 213 - acute inflammation
Suppurative bronchopneumonia. 10 months old.
PB 24075 Gene:
ectodysplasin-A
Eda

Pathology:
MPATH 26 - alopecia
MPATH 58 - aplasia
Skin X-linked ectodermal dysplasia and alopecia
PB 24076 Gene:
ectodysplasin-A
Eda

Pathology:
MPATH 58 - aplasia
Footpad X-linked ectodermal dysplasia. The image shows aplasia of eccrine glands due to mutation of the ectodysplasin gene (Tabby).
PB 24098 Gene:
N/A

Pathology:
MPATH 64 - developmental dysplasia
Dental dysplasia in the upper incisor showing secondary fibrosis in the pulp and partially mineralised enamel matrix.
PB 24099 Gene:
N/A

Pathology:
MPATH 64 - developmental dysplasia
Dental dysplasia in the upper incisor showing secondary fibrosis in the pulp and partially mineralised enamel matrix.
PB 24100 Gene:
N/A

Pathology:
MPATH 64 - developmental dysplasia
Coronal section through head of a 14 day old mouse showing on the right hand side mild dental dysplasia in the upper incisor and normal development on the left.
PB 24101 Gene:
N/A

Pathology:
MPATH 64 - developmental dysplasia
Mild dental dysplastic lesion with invagination of the enamel.
PB 24133 Gene:
Igf2
Trp53

Pathology:
MPATH 55 - developmental and structural abnormality
MPATH 76 - heterotopia
Ectopic crypts in a P53 knockout mouse expressing Igf2 from a cytokeratin promoter
PB 24137 Gene:
HRAS

Pathology:
MPATH 64 - developmental dysplasia
Dental dysplasia in a six month old male
PB 24138 Gene:
HRAS

Pathology:
MPATH 64 - developmental dysplasia
Dental dysplasia in a 6 month old male
PB 24172 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Spontaneous Fibro-osseous lesions in the femur of a two year old female B6C3F1 mouse. The lesion occurs spontaneously in 40-100% of female B6C3F1 mice and less
than 1% of males.
PB 24173 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Spontaneous Fibro-osseous lesions in the femur of a two year old female B6C3F1 mouse. The lesion occurs spontaneously in 40-100% of female B6C3F1 mice and less
than 1% of males.
PB 24174 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Spontaneous Fibro-osseous lesions in the femur of a two year old female B6C3F1 mouse. The lesion occurs spontaneously in 40-100% of female B6C3F1 mice and less
than 1% of males.
PB 24176 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Spontaneous Fibro-osseous lesions in the cranium of a two year old female B6C3F1 mouse. The lesion occurs spontaneously in 40-100% of female B6C3F1 mice and less
than 1% of males.
PB 24177 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Spontaneous Fibro-osseous lesions in the cranium of a two year old female B6C3F1 mouse. The lesion occurs spontaneously in 40-100% of female B6C3F1 mice and less
than 1% of males.
PB 24178 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Spontaneous Fibro-osseous lesions in the cranium of a two year old female B6C3F1 mouse. The lesion occurs spontaneously in 40-100% of female B6C3F1 mice and less
than 1% of males.
PB 24179 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Spontaneous Fibro-osseous lesions in the cranium of a two year old female B6C3F1 mouse. The lesion occurs spontaneously in 40-100% of female B6C3F1 mice and less
than 1% of males.
PB 24180 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Spontaneous Fibro-osseous lesions in the cranium of a two year old female B6C3F1 mouse. The lesion occurs spontaneously in 40-100% of female B6C3F1 mice and less
than 1% of males.
PB 24181 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Spontaneous Fibro-osseous lesions in the cranium of a two year old female B6C3F1 mouse. The lesion occurs spontaneously in 40-100% of female B6C3F1 mice and less
than 1% of males.
PB 24182 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Fibro-osseous lesions in the femur of a two year old female B6C3F1 mouse treated with Vanadium pentoxide. It is likely that these are spontaneous background lesions rather than caused by the treatment. The lesion occurs spontaneously in 40-100% of fe ...
PB 24183 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Fibro-osseous lesions in the femur of a two year old female B6C3F1 mouse treated with Vanadium pentoxide. It is likely that these are spontaneous background lesions rather than caused by the treatment. The lesion occurs spontaneously in 40-100% of fe ...
PB 24184 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Fibro-osseous lesions in the femur of a two year old female B6C3F1 mouse treated with Vanadium pentoxide. It is likely that these are spontaneous background lesions rather than caused by the treatment. The lesion occurs spontaneously in 40-100% of fe ...
PB 24185 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Fibro-osseous lesions in the cranium of a two year old female B6C3F1 mouse treated with Vanadium pentoxide. It is likely that these are spontaneous background lesions rather than caused by the treatment. The lesion occurs spontaneously in 40-100% of ...
PB 24186 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Fibro-osseous lesions in the cranium of a two year old mouse treated with Vanadium pentoxide. It is likely that these are spontaneous background lesions rather than caused by the treatment.
PB 24187 Gene:
N/A

Pathology:
MPATH 590 - fibro-osseous lesion
Fibro-osseous lesions in the cranium of a two year old female B6C3F1 mouse treated with Vanadium pentoxide. It is likely that these are spontaneous background lesions rather than caused by the treatment. The lesion occurs spontaneously in 40-100% of ...
PB 24190 Gene:
Mdr
Msh2

Pathology:
MPATH 134 - hyperplasia
Oval cell hyperplasia
PB 34192 Gene:
N/A

Pathology:
MPATH 134 - hyperplasia
Adrenal Medullary hyperplasia
PB 34208 Gene:
N/A

Pathology:
MPATH 134 - hyperplasia
Pancreatic endocrine hyperplasia
PB 94247 Gene:
N/A

Pathology:
MPATH 76 - heterotopia
Heterotopic adrenal cortex
PB 94256 Gene:
N/A

Pathology:
MPATH 181 - fibrosis
MPATH 196 - dermatitis
`B6 dermatitis` Hair thinning on the midback 3.0cm x 1.5cm to sacral area.
PB 94259 Gene:
N/A

Pathology:
MPATH 76 - heterotopia
Ectopic adrenal cortex
PB 94272 Gene:
N/A

Pathology:
MPATH 14 - process of degenerative change
Senescent `joint mice` showing degenerative change of the temporomandibular joint.
PB 94273 Gene:
N/A

Pathology:
MPATH 14 - process of degenerative change
Senescent `joint mice` showing degenerative change of the temporomandibular joint.
PB 94274 Gene:
N/A

Pathology:
MPATH 14 - process of degenerative change
Senescent `joint mice` showing degenerative change of the temporomandibular joint.
PB 94275 Gene:
N/A

Pathology:
MPATH 14 - process of degenerative change
Senescent `joint mice` showing degenerative change of the temporomandibular joint.
PB 94276 Gene:
N/A

Pathology:
MPATH 14 - process of degenerative change
Senescent `joint mice` showing degenerative change of the temporomandibular joint.
PB 94285 Gene:
N/A

Pathology:
MPATH 14 - process of degenerative change
A poorly differentiated sarcoma, possibly a rhabdomyosarcoma, probably arising from where the dorsal skeletal muscles over/around the spinal cord enter the spinal canal, and compress the cord causing severe degenerative changes that would explain the ...
PB 94296 Gene:
N/A

Pathology:
MPATH 214 - chronic inflammation
Chronic inflammation of the anterior pituitary gland (adenohypophysis).
PB 94297 Gene:
N/A

Pathology:
MPATH 214 - chronic inflammation
Chronic inflammation of the anterior pituitary gland (adenohypophysis).
PB 94298 Gene:
N/A

Pathology:
MPATH 214 - chronic inflammation
Chronic inflammation of the anterior pituitary gland (adenohypophysis).
PB 94299 Gene:
N/A

Pathology:
MPATH 589 - dysplasia
Dental dysplasia
PB 94300 Gene:
N/A

Pathology:
MPATH 589 - dysplasia
Dental dysplasia
PB 94301 Gene:
N/A

Pathology:
MPATH 589 - dysplasia
Dental dysplasia
PB 94302 Gene:
N/A

Pathology:
MPATH 589 - dysplasia
Dental dysplasia
PB 94303 Gene:
N/A

Pathology:
MPATH 589 - dysplasia
Dental dysplasia
PB 94304 Gene:
N/A

Pathology:
MPATH 589 - dysplasia
Dental dysplasia
PB 94340 Gene:
N/A

Pathology:
MPATH 195 - arthritis
`Stifle joint mouse`

While there is no inflammation in the knee joint and therefore not a true arthritis, there are massive abnormalities of the articular cartilage where there is total loss of cartilage at the articular surface, a joi ...
PB 94341 Gene:
N/A

Pathology:
MPATH 195 - arthritis
`Stifle joint mouse`

While there is no inflammation in the knee joint and therefore not a true arthritis, there are massive abnormalities of the articular cartilage where there is total loss of cartilage at the articular surface, a joi ...
PB 94342 Gene:
N/A

Pathology:
MPATH 195 - arthritis
`Stifle joint mouse`

While there is no inflammation in the knee joint and therefore not a true arthritis, there are massive abnormalities of the articular cartilage where there is total loss of cartilage at the articular surface, a joi ...
PB 94368 Gene:
N/A

Pathology:
MPATH 213 - acute inflammation
Foreign body periodontis, acute inflammation.
PB 94534 Gene:
N/A

Pathology:
MPATH 586 - polycystic disease
This is the gall bladder from a 662 day old male C57BLKS/J mouse. Note the polycystic nature of the gall bladder wall. The cysts contain amphophilic material possible concretions.
PB 94535 Gene:
N/A

Pathology:
MPATH 586 - polycystic disease
MPATH 614 - concretion
This is the gall bladder from a 662 day old male C57BLKS/J mouse. Note the polycystic nature of the gall bladder wall. The cysts contain amphophilic material possible concretions.
PB 94536 Gene:
N/A

Pathology:
MPATH 586 - polycystic disease
This is the gall bladder from a 662 day old male C57BLKS/J mouse. Note the polycystic nature of the gall bladder wall. The cysts contain amphophilic material possible concretions.
PB 94545 Gene:
N/A

Pathology:
MPATH 640 - osteoid deposition
This is the skin from a 662 day old C57BLKS/J male mouse. Note the presence of bone in the dermis of the skin. This is ectopic bone.
PB 94546 Gene:
N/A

Pathology:
MPATH 640 - osteoid deposition
This is the skin from a 662 day old C57BLKS/J male mouse. Note the presence of bone in the dermis of the skin. This is ectopic bone.
PB 94547 Gene:
N/A

Pathology:
MPATH 134 - hyperplasia
This is the pancreas from a 856 day old male 129S1/SvlmJ mouse. Note the pancreatic islets, while appearing to be normal, are unusually large. This is pancreatic islet hyperplasia, a common finding, albeit not always this large, in mice 20 months of ...
PB 94575 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
MPATH 213 - acute inflammation
This is the nail unit from a 837 day old male NON/ShiLtJ mouse. Note the nail plate did not form normally. There is various degrees of acute inflammation along the length of the nail plate and bed to the hyponychium. This is nail dystrophy.
PB 94576 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
MPATH 213 - acute inflammation
This is the nail unit from a 837 day old male NON/ShiLtJ mouse. Note the nail plate did not form normally. There is various degrees of acute inflammation along the length of the nail plate and bed to the hyponychium. This is nail dystrophy.
PB 94577 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
MPATH 213 - acute inflammation
This is the nail unit from a 837 day old male NON/ShiLtJ mouse. Note the nail plate did not form normally. There is various degrees of acute inflammation along the length of the nail plate and bed to the hyponychium. This is nail dystrophy.
PB 94578 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
MPATH 213 - acute inflammation
This is the nail unit from a 837 day old male NON/ShiLtJ mouse. Note the nail plate did not form normally. There is various degrees of acute inflammation along the length of the nail plate and bed to the hyponychium. This is nail dystrophy.
PB 94616 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
MPATH 579 - ulcer
This was the nail unit from a 626 day old female MRL/MpJ mouse. The nail is dystrophic and the hyponychium is ulcerated and severely inflammed.
PB 94617 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
MPATH 579 - ulcer
This was the nail unit from a 626 day old female MRL/MpJ mouse. The nail is dystrophic and the hyponychium is ulcerated and severely inflammed.
PB 94618 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
MPATH 579 - ulcer
This was the nail unit from a 626 day old female MRL/MpJ mouse. The nail is dystrophic and the hyponychium is ulcerated and severely inflammed.
PB 94619 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
MPATH 579 - ulcer
This was the nail unit from a 626 day old female MRL/MpJ mouse. The nail is dystrophic and the hyponychium is ulcerated and severely inflammed.
PB 94620 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
MPATH 579 - ulcer
This was the nail unit from a 626 day old female MRL/MpJ mouse. The nail is dystrophic and the hyponychium is ulcerated and severely inflammed.
PB 94621 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
MPATH 579 - ulcer
This was the nail unit from a 626 day old female MRL/MpJ mouse. The nail is dystrophic and the hyponychium is ulcerated and severely inflammed.
PB 94652 Gene:
N/A

Pathology:
MPATH 201 - vasculitis
This is a large artery within the adventia of the duodenum. Note the irregular walls and chronic lymphocytic infiltrates in the wall. Multiple sites were involved. This is a form of polyarteritis nodosa that is not infrequent in C57 substrains.
PB 94664 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
This is the muzzle from a 380 day old female FVB/NJ mouse. There are two vibrissae that are deformed. This is follicular dystrophy of the vibrissae.
PB 94665 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
This is the muzzle from a 380 day old female FVB/NJ mouse. There are two vibrissae that are deformed. This is follicular dystrophy of the vibrissae.
PB 94666 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
This is the muzzle from a 380 day old female FVB/NJ mouse. There are two vibrissae that are deformed. This is follicular dystrophy of the vibrissae.
PB 94667 Gene:
N/A

Pathology:
MPATH 640 - osteoid deposition
This is the kidney from a 375 day old female C3H/HeJ mouse. Note the pink mass which is osteoid or ectopic bone formation.
PB 94668 Gene:
N/A

Pathology:
MPATH 640 - osteoid deposition
This is the kidney from a 375 day old female C3H/HeJ mouse. Note the pink mass which is osteoid or ectopic bone formation.
PB 94677 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
Nail dystrophy.
PB 94678 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
Nail dystrophy.
PB 94679 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
Nail dystrophy.
PB 94680 Gene:
N/A

Pathology:
MPATH 589 - dysplasia
Nail dysplasia.
PB 94681 Gene:
N/A

Pathology:
MPATH 589 - dysplasia
Nail dysplasia.
PB 94682 Gene:
N/A

Pathology:
MPATH 589 - dysplasia
Nail dysplasia.
PB 94683 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
Nail dystrophy.
PB 94684 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
Nail dystrophy.
PB 94685 Gene:
N/A

Pathology:
MPATH 554 - dystrophy
Nail dystrophy.
PB 94696 Gene:
N/A

Pathology:
MPATH 145 - fat cell hyperplasia
MPATH 127 - atrophy
This is the pancreas from a 605 day old male MRL/MpJ mouse. Most of the pancreatic acinar tissue is missing and has been replaced by white adipose tissue.
PB 94705 Gene:
N/A

Pathology:
MPATH 181 - fibrosis
This is the heart from a 792 day old male C57BL/10J mouse. There is extensive myocardial and epicardial mineralization (purple crystals) and fibrosis.
PB 94706 Gene:
N/A

Pathology:
MPATH 181 - fibrosis
This is the heart from a 792 day old male C57BL/10J mouse. There is extensive myocardial and epicardial mineralization (purple crystals) and fibrosis.
PB 94707 Gene:
N/A

Pathology:
MPATH 181 - fibrosis
This is the heart from a 792 day old male C57BL/10J mouse. There is extensive myocardial and epicardial mineralization (purple crystals) and fibrosis.
PB 94708 Gene:
N/A

Pathology:
MPATH 181 - fibrosis
This is the heart from a 792 day old male C57BL/10J mouse. There is extensive myocardial and epicardial mineralization (purple crystals) and fibrosis.
PB 94709 Gene:
N/A

Pathology:
MPATH 181 - fibrosis
This is the heart from a 792 day old male C57BL/10J mouse. There is extensive myocardial and epicardial mineralization (purple crystals) and fibrosis.
PB 94713 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
alpha-irradiation of bone by Th227 injection
PB 94714 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
Osteosarcoma (fibroblastic) at dorsal of 2.-5. lumbar vertebrae

Tumor induction after alpha-irradiation of bone using Thorium227 injection
PB 94715 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (High-grade, well-structured, osteoid-rich) proximal Tibia

Tumor induction after alpha-irradiation of bone using Thorium227 injection
PB 94716 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (High-grade, well-structured, osteoid-rich) proximal Tibia

Tumor induction after alpha-irradiation of bone using Thorium227 injection
PB 94717 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (High-grade, well-structured) originating from lumbar vertebrae, with infiltration of spinal nerve

Tumor induction after alpha-irradiation of bone using Thorium227 injection
PB 94718 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (High-grade, well-structured) originating from lumbar vertebrae, with infiltration of spinal nerve

Tumor induction after alpha-irradiation of bone using Thorium227 injection
PB 94719 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (High-grade, well-structured) originating from lumbar vertebrae, beginning compression of spinal nerve

Tumor induction after alpha-irradiation of bone using Thorium227 injection

Sekt.Nr.08/1220 ...
PB 94720 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (High-grade, well-structured) originating from lumbar vertebrae, beginning compression of spinal nerve

Tumor induction after alpha-irradiation of bone using Thorium227 injection

Sekt.Nr.08/1220 ...
PB 94721 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (High-grade, well-structured) originating from sternal vertebrae

Tumor induction after alpha-irradiation of bone using Thorium227 injection

Sekt.Nr.08/1220.5
PB 94722 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (High-grade, well-structured) originating from sternal vertebrae

Tumor induction after alpha-irradiation of bone using Thorium227 injection

Sekt.Nr.08/1220.5
PB 94723 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (well-structured, osteoid-rich) originating from thoracic vertebral column, invading spinal nerve and compressing opposite vertebrae

Tumor induction after alpha-irradiation of bone using Thorium227 injection< ...
PB 94724 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (well-structured, osteoid-rich) originating from thoracic vertebral column, invading spinal nerve and compressing opposite vertebrae

Tumor induction after alpha-irradiation of bone using Thorium227 injection< ...
PB 94725 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
Metastasis of an osteoblastic Osteosarcoma (well-structured, osteoid-rich) in spleen

Tumor induction after alpha-irradiation of bone using Thorium227 injection

Sekt.Nr.08/1573
PB 94726 Gene:
Rb1

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (high-grade, well-structured, osteoid-rich) in skull/scalp

Tumor induction after alpha-irradiation of bone using Thorium227 injection

Sekt.Nr.08/1573x
PB 94727 Gene:
N/A

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (High-grade, well-structured, osteoid-rich) proximal Tibia

X-ray image of tumor PB 94715/94716

Tumor induction after alpha-irradiation of bone using Thorium227 injection
PB 94728 Gene:
N/A

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (High-grade, well-structured) originating from lumbar vertebrae, with infiltration of spinal nerve

X-ray image of tumor PB 94717/94718

Tumor induction after alpha-irradiation of bone using Thori ...
PB 94729 Gene:
N/A

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (High-grade, well-structured) originating from lumbar vertebrae, beginning compression of spinal nerve

X-ray image of tumor PB 94719/94720

Tumor induction after alpha-irradiation of bone using T ...
PB 94730 Gene:
N/A

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (well-structured, osteoid-rich) in skull (HE Histology PB 94726)

Metastasis in spleen (HE Histology PB 94725)

Osteosarcoma in sacral bone

Tumor induction after alpha-irradiation o ...
PB 94731 Gene:
N/A

Pathology:
MPATH 606 - neoplasia
Osteosarcoma (fibroblastic) at dorsal of 2.-5. lumbar vertebrae

X-ray image of tumor PB 94713/94714

Tumor induction after alpha-irradiation of bone using Thorium227 injection

Sekt.Nr.08/778
PB 94732 Gene:
N/A

Pathology:
MPATH 606 - neoplasia
Osteoblastic Osteosarcoma (well-structured, osteoid-rich) originating from thoracic vertebral column, invading spinal nerve and compressing opposite vertebrae

X-ray image of tumor PB 94723/94724

Tumor induction after alp ...

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