|Pathbase Image PB 94732 submitted by helmholtz center munich, inst f radiation biology on 2011-12-22|
|EMAP / Embryonic stage, |
tissue or post-natal age:
|Genotype Status:||Rb1-LoxP/+ x Cre+ |
|MPATH / Pathology:||MPATH 606 - neoplasia|
|Genetic Manipulation:||bone conditional Rb1 del(Ex19) under Col1a1-Cre control |
|MA / Anatomical Site:||MA 1430 - lumbar vertebra 3|
|Designated Allele Name:|
|Experimental Manipulation:||Radiation |
|Description:||Osteoblastic Osteosarcoma (well-structured, osteoid-rich) originating from thoracic vertebral column, invading spinal nerve and compressing opposite vertebrae|
X-ray image of tumor PB 94723/94724
Tumor induction after alpha-irradiation of bone using Thorium227 injection
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