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Pathbase: PB 94730

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Pathbase Image PB 94730 submitted by helmholtz center munich, inst f radiation biology on 2011-12-22
Sex:Female
Gene:
Strain:FVB/N
Organism:Mouse
EMAP / Embryonic stage,
tissue or post-natal age:
Genotype Status:Rb1-LoxP/+ x Cre+
MPATH / Pathology:MPATH 606 - neoplasia
Genetic Manipulation:bone conditional Rb1 del(Ex19) under Col1a1-Cre control
MA / Anatomical Site:MA 1432 - lumbar vertebra 5
Designated Allele Name:
Experimental Manipulation:Radiation
Description:Osteoblastic Osteosarcoma (well-structured, osteoid-rich) in skull (HE Histology PB 94726)

Metastasis in spleen (HE Histology PB 94725)

Osteosarcoma in sacral bone

Tumor induction after alpha-irradiation of bone using Thorium227 injection

Sekt.Nr.08/1573


Magnification:
Stain:X-ray


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