PB 3498
Description
Complex tubular mammary gland adenocarcinoma. 6.5 months old. Note that transgenic construct expresses Human transforming growth factor alpha.
MPATH / Pathology
MPATH 268 - adenocarcinoma
Gene
TGFA
sex
Female
strain
B6D2-TgN(MMTV-TGFA)29Rjc
organism
Mouse
EMAP / Embryonic stage, tissue or post-natal age:
99996 - Sexually mature
genotype status
Hemizygous
genetic manipulation
Transgenic-Overexpression
MA / Anatomical Site
MA 145 - mammary gland
Designated Allele Name
Experimental Manipulation
Further info
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Copyright
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Gene Ontology
GO ID: 0004713 - protein tyrosine kinase activity GO ID: 0004871 - signal transducer activity GO ID: 0005155 - epidermal growth factor receptor activating ligand activity GO ID: 0005515 - protein binding GO ID: 0005615 - extracellular space GO ID: 0005886 - plasma membrane GO ID: 0005887 - integral to plasma membrane GO ID: 0007267 - cell-cell signaling GO ID: 0008283 - cell proliferation