|Pathbase Image PB 3436 submitted by Pathbase on 2003-07-10|
|EMAP / Embryonic stage, |
tissue or post-natal age:
|99998 - Adult|
|Genotype Status:||Hemizygous |
|MPATH / Pathology:||MPATH 451 - transitional cell carcinoma|
|Genetic Manipulation:||Transgenic |
|MA / Anatomical Site:||MA 380 - urinary bladder|
|Designated Allele Name:|
|Description:||Urinary bladder transitional cell carcinoma. C57BL/6-TgN(Amy1TAg)501Knw mice are viable and fertile. They express the SV40 tumor antigen under control of the liver promoter of the mouse alpha-amylase gene (Amy-1a). This transgenic strain develops metastatic osteosarcomas at about 13 months of age.|
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