Description

Footpad X-linked ectodermal dysplasia. The image shows aplasia of eccrine glands due to mutation of the ectodysplasin gene (Tabby).

MPATH / Pathology

MPATH 58 - aplasia

Gene

Eda
ectodysplasin-A

sex

Male

strain

B6CBACa A^w-J/A-Eda^Ta/Y

organism

Mouse

EMAP / Embryonic stage, tissue or post-natal age:

genotype status

Hemizygous

genetic manipulation

Spontaneous-mutant

MA / Anatomical Site

MA 694 - limb skin

Designated Allele Name

Ta
tabby

Experimental Manipulation

Further info

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Copyright

This image remains the property of the originating Institution and should not be modified, reproduced or disseminated without the express permission of the submitter.

Gene Ontology

GO ID: 0005164 - tumor necrosis factor receptor binding GO ID: 0005789 - endoplasmic reticulum membrane GO ID: 0005887 - integral to plasma membrane GO ID: 0006955 - immune response GO ID: 0007160 - cell-matrix adhesion GO ID: 0007275 - development GO ID: 0007431 - salivary gland development GO ID: 0016020 - membrane GO ID: 0016021 - integral to membrane GO ID: 0030154 - cell differentiation GO ID: 0042346 - positive regulation of NF-kappaB protein-nucleus import GO ID: 0045177 - apical part of cell

Search PubMed:

PubMed number: 12692542

MGI:

Gene: ectodysplasin-A

MGI:

Gene: Eda