Pathbase: PB 154


Pathbase Image PB 154 submitted by University of Cambridge on 2001-09-25
EMAP / Embryonic stage,
tissue or post-natal age:
99998 - Adult
Genotype Status:Homozygous
MPATH / Pathology:MPATH 62 - cyst
MPATH 547 - mucous secretions
Genetic Manipulation:Gene-knockout-mutation
MA / Anatomical Site:MA 338 - duodenum
Designated Allele Name:
Experimental Manipulation:
Description:Duodenum from mice carrying the most common mutation in cystic fibrosis (CF), delta F508, within the cystic fibrosis (Cftr) gene.


Further Information
Gene Ontology Terms associated with the genes involved in this lesion may be searched on AMIGO by clicking on each GO ID number below:
Search AmiGO:GO ID: 0005224 - ATP-binding and phosphorylation-dependent chloride channel activity
Search AmiGO:GO ID: 0005254 - chloride channel activity
Search AmiGO:GO ID: 0005886 - plasma membrane
Search AmiGO:GO ID: 0005887 - integral to plasma membrane
Search AmiGO:GO ID: 0006832 - small molecule transport
Search AmiGO:GO ID: 0007125 - invasive growth
Search AmiGO:GO ID: 0007585 - respiratory gaseous exchange
Search the Mouse Phenome Database:MPD number: 2476
Search PubMed:PubMed number: 7545494
Search MGI@Jax:Gene: Cftr
Images of the same study:Study number: 3
NOTE: Not all terms are currently shared between Pathbase and the above databases, some searches may not produce returns, in which case users should use synonyms or more inclusive text terms to search manually!

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