|Pathbase Image PB 153 submitted by University of Cambridge on 2001-09-25|
|EMAP / Embryonic stage, |
tissue or post-natal age:
|99998 - Adult|
|Genotype Status:||Homozygous |
|MPATH / Pathology:||MPATH 62 - cyst|
MPATH 547 - mucous secretions
|Genetic Manipulation:||Gene-knockout-mutation |
|MA / Anatomical Site:||MA 335 - colon|
|Designated Allele Name:|
|Description:||Cystic fibrosis in mutant colon in Cftrtm2Cam mice carrying the most common mutation in cystic fibrosis (CF), delta F508, within the cystic fibrosis (Cftr) gene. Crypt distention and mucus hyperaccumulation noted|
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