Pathbase

Pathbase: PB 13666

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Pathbase Image PB 13666 submitted by Pathbase on 2003-08-28
Sex:Unknown
Gene:retina and anterior neural fold homeobox
Rax
Strain:ZRDCT-AN-Raxey1
Organism:Mouse
EMAP / Embryonic stage,
tissue or post-natal age:
Genotype Status:Homozygous
MPATH / Pathology:MPATH 58 - aplasia
MPATH 473 - developmental cystic dysplasia
Genetic Manipulation:Spontaneous-mutant
MA / Anatomical Site:MA 275 - lens
Designated Allele Name:eyeless 1
ey1
retina and anterior neural fold homeobox
Experimental Manipulation:
Description:Open lens vesicle. 90% of homozygous mice are anophthalmic.


Magnification:10
Stain:H&E


Further Information
Gene Ontology Terms associated with the genes involved in this lesion may be searched on AMIGO by clicking on each GO ID number below:
Search AmiGO:GO ID: 0003677 - DNA binding
Search AmiGO:GO ID: 0003700 - transcription factor activity
Search AmiGO:GO ID: 0005634 - nucleus
Search AmiGO:GO ID: 0005667 - transcription factor complex
Search AmiGO:GO ID: 0006355 - regulation of transcription, DNA-dependent
Search AmiGO:GO ID: 0007275 - development
Search MGI@Jax:Gene: Rax
Search MGI@Jax:Gene: retina and anterior neural fold homeobox
NOTE: Not all terms are currently shared between Pathbase and the above databases, some searches may not produce returns, in which case users should use synonyms or more inclusive text terms to search manually!


Copyright
This image remains the property of the originating Institution and should not be modified, reproduced or disseminated without the express permission of the submitter.




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