PB 1235
Description
Multiform fibrosarcomas in male mouse with targeted deletion of Ptch after irradiation with 3 Gy of X-rays.
MPATH / Pathology
MPATH 406 - dermatofibrosarcoma
Gene
Ptch
sex
Male
strain
(129SV-Ptchtm1Zim;C57BL/6); CD1
organism
Mouse
EMAP / Embryonic stage, tissue or post-natal age:
99998 - Adult
genotype status
Heterozygous
genetic manipulation
Gene-knockout-deletion
MA / Anatomical Site
MA 517 - trunk skin
Designated Allele Name
Ptch
Patched
Experimental Manipulation
Radiation
Further info
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Copyright
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Gene Ontology
GO ID: 0005887 - integral to plasma membrane GO ID: 0007226 - regulation of smoothened receptor by patched GO ID: 0008158 - patched receptor activity GO ID: 0016021 - integral to membrane GO ID: 0030326 - limb morphogenesis GO ID: 0040015 - negative regulation of body size